Fine and Pharmaceutical Chemistry

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CDMO

M2i Group offers custom synthesis services designed to seamlessly integrate all stages of chemical development: from the design of an original synthetic route with the delivery of a few grams, to the supply of pilot batches following industrial process optimization, and GMP production of several tons of product, as well as the preparation of the regulatory dossier.Our custom synthesis activity has been designed to seamlessly integrate all phases of chemical development: from designing an original synthesis route and supplying a few grams, to providing pilot batches following industrial process development, GMP production of several tons of product, and preparing the regulatory dossier.

Services

We place our expertise and services at the disposal of external partners, whether for the custom design of tailor-made molecules or through collaborations aimed at developing new and innovative projects. Thanks to our mastery of chemical processes and our adaptability, we support our clients at every stage, from the initial idea to industrial implementation.

  • Proprietary molecules in catalog (APIs, intermediates, pheromones & specialty molecules)
  • CRO – Contract Research (flexible, outsourced research contracts managed on an FTE basis)
  • Contract development & manufacturing (process development, industrialization & production)
  • Consulting / Support (R&D, innovation, key sourcing and industrial strategy)

Organic Polymer Chemistry

M2i also offers its expertise in polymer chemistry and formulation at any stage of project development, from the synthesis of a few grams to several kilograms.

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Catalogue

We possess in-depth expertise in the design and manufacture of a wide range of specific pharmaceutical molecules, meeting the strictest requirements for quality, performance, and regulatory compliance.

Molecules

  • Pinaverium Bromide
  • Trithioanisole
  • Myrtecaïne
  • Myrtecaïne Lauryl Sulfate
  • Diphenhydramine Methysulfate
  • Veratole

Building blocks and intermediates

  • Bromomethyl cyclopropane
  • Cyclobutane carbonyl chloride
  • Cyclobutane carboxaldehyde
  • Bromothiophene
  • N-trifluoroacetyl-l-lysine
  • 4-chlorobutyl-veratate

Development

  • Metopimazine
  • Selachyl alcohol
  • Guaiacol

Pharmaceutical Actives

M2i also has an extensive portfolio of proprietary products, developed in-house thanks to its scientific and technological expertise.

Pharmaceutical actives

  • Alkylation (dimethyl sulfate)

  • Amidation

  • Phase transfer catalysis

  • Bromination (Br₂, HBr, …)

  • Chlorination (SOCl₂, Cl₂, POCl₃)

  • Cyanation

  • Chemical resolution

  • Hydrides (LiH, NaH, KH)

  • Esterification

  • Friedel–Crafts

  • Grignard

  • Continuous process

  • Wittig reaction

  • Coupling reactions (Fe, Cu)

  • Hoffman rearrangement

  • Reduction (NaBH₄, AlLiH₄, Vitride)

  • Saponification

  • Sulfuration (H₂S, S₈)

  • Oxidation (H₂O₂)

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Specific Technologies

Bromine chemistry associated with cyanation, sulfur and mercaptan chemistry, deprotonation by hydrides, highly energetic chlorinations by POCl3, cyclopropane and cyclobutane chemistry.