Chemistry & Life Science

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CDMO CDRO Industry

Our custom synthesis activity has been designed to seamlessly integrate all phases of chemical development: from designing an original synthesis route and supplying a few grams, to providing pilot batches following industrial process development, GMP production of several tons of product, and preparing the regulatory dossier.

Organic Chemistry

M2i also offers its expertise in organic chemistry and surfactant chemistry, tailored for earlier-stage projects and development phases, through flexible and manageable FTE-based services.

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Synthesis

We possess in-depth expertise in the design and manufacture of a wide range of specific pharmaceutical molecules, meeting the strictest requirements for quality, performance, and regulatory compliance.

Molecules

  • Pinaverium Bromide
  • Trithioanisole
  • Myrtecaïne
  • Myrtecaïne Lauryl Sulfate
  • Diphenhydramine Methysulfate
  • Veratole

Building blocks and intermediates

  • Bromomethyl cyclopropane
  • Cyclobutane carbonyl chloride
  • Cyclobutane carboxaldehyde
  • Bromothiophene
  • N-trifluoroacetyl-l-lysine
  • 4-chlorobutyl-veratate

Development

  • Metopimazine
  • Selachyl alcohol
  • Guaiacol

Pharmaceutical Actives

M2i also has an extensive portfolio of proprietary products, developed in-house thanks to its scientific and technological expertise.

Pharmaceutical actives

  • Alkylation (dimethyl sulfate)
  • Amidation
  • Phase transfer catalysis
  • Bromination (Br2, HBr,..)
  • Chlorination (SOCl2, Cl2, POCl2)
  • Cyanation
  • Chemical resolution
  • Hydrides (LiH, NaH, KH)
  • Esterification
  • Friedel&crafts
  • Grignard
  • Continuous process
  • Wittig reaction
  • Coupling reactions (Fe, Cu)
  • Hoffman rearrangement
  • Reduction (NaBH4, AlLiH4, Vitride)
  • Saponification
  • Sulfuration (H2S, S8)
  • Oxidation (H2O2)
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Specific Technologies

Bromine chemistry associated with cyanation, sulfur and mercaptan chemistry, deprotonation by hydrides, highly energetic chlorinations by POCl3, cyclopropane and cyclobutane chemistry.

Services

We make our expertise and services available to external partners, whether for custom molecule design or for collaborations aimed at developing new innovative projects. Thanks to our mastery of chemical processes and our adaptability, we support our clients at every step, from the initial idea to industrial implementation.

  • Proprietary molecules from catalog (APIs, intermediates, pheromones & specialty molecules)
  • CRO – Contract Research (outsourced research contract)
  • Contract development & production (process development, industrialization & production)
  • Consulting / support (R&D, innovation, key sourcing and industrial strategy)